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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d1e06b50b32ad07e7f624c4ef080180e0ce9808afdefd8b28d63bbe92482a4' 
  AND token = 'oeFZ8SD5Eqg00PGtJqwIE4vyq2V3F3v53HnvsR+SC34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}