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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6815c6085a4463e6893a1eb12376e128986dc3060a11f2ee0a0e0a94f249af74' 
  AND token = 'ouHVK8srh68B7SUd7Y2xrqD3xkLDLVBVh27J5xuEBGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}