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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8668084a2a36c184c5a959f53fbc584c4b63774d08fb666c0263b66feed8395e' 
  AND token = '0hRmV2+y7TqAQkIdjs7L6EGaBXjzFWnu6qZ5U4G69NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}