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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a05496091607c4f4fe68d8e6c41e507748cb3d7e0f692144bab364069cc38c0' 
  AND token = 'RASuUdGUeRr3ihFtI21TG6vG+RLjBUmgYq4md2PCdec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}