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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad3a6db1c6d1ebcbcf9801ff9bec4e40224c35dd1f3b7beb0ceca7da603555f' 
  AND token = '681EaAsgeMXAKjd4Ut1WEcmjkGk3Bb5AZ94RyP7U1ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}