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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1cf8ce37743d1490e0c2a877872c2684d8192e9fbf9cae1f412edf67255c61e' 
  AND token = 'eouMDMJzMtg9nv+Z75x5vLynrxsTc7F3vSdMX9bYgeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}