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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '239f7bb70aba9d37273ca1ad9e0428de28f22027d30b51bec94cce3a8355e8b3' 
  AND token = 'TxyV70/kmMB69PJX5rYDrDT21v/dKfOzgEMlXOqFDIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}