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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '752516ea79b2a29759efa3e427ace278b3c82777bddbc2e4486fb7e0ca43b29f' 
  AND token = '863eDOg9KE/2yQEDxsuF2LrQUpcXM+/VSWqU4dSGgk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}