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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1112dc908788e094dbc64c9529ebd15c69dffe7e705ace7774d9a53e0d0b8d9d' 
  AND token = 'e6/sQ6NHb1yJ8BJxtvavg2RYhSx8wxmEpgUsw32fRgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}