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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c321a8ee8b32735ce61055b8428066e011b6c7d707ad3f2333ab84359ab07c5' 
  AND token = 'w8/uqfz8CupejdZae2kdamPKOWtKTm00yBFkNPlJmpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}