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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f49c885bbdcef956d4844c6bc861719e0b73035e565103eccf0531cd40cd0d2' 
  AND token = 'Y4CuWB8/GEPw9TCi5pjsH+RtarXlOU1eMHU7S3p3cPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}