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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1741cddb289d36310145d7370bcc0670065c0c7aab5ba129b56189c3fcb2e336' 
  AND token = 'Vtw6IDSYtIvGDJs6Syse/zOXVlAX/9QzUpzQHg7tjYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}