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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65009fbab7974b4ab546488912e0b1e41eb1da5d629a7de16320eb6b648a6ed' 
  AND token = 'jyoC9Q9uqPiL8V1TLHhYeJ1YU+RavKABVQ4ml4KIbqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}