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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4006b94053eba84185a7cd73c433b9595aaf649746ca9022a1f1e1baf93577' 
  AND token = 'BVqSBBnA2Rn8ykJWpmVun7lH2lpLc4CCTwT0JzbdC8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}