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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd494ba3cb0b2e24834d83cf96f3d3f6e37872677ee2b4ea231097173bffc443' 
  AND token = 'lSpxD4ylUL7D7JmcYiRm2M786AvsxGtYS4+gVD2b2+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}