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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7386032986ca67f33bca119c666a90bebb4107d9d2ea0cbf98864c9567d82afa' 
  AND token = 'UQmc2v+ZY73hghaJj+vZ7SIYE4MSqbCAifD7i0PfSDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}