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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eec0ffde43127eeea6022e33b04fba0fd0e258f5613739321d93e89f41796d14' 
  AND token = 'zVJfMyRI7Ixv7f2xQ58g26XzwBG2Dc6RltYGG68Wh5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}