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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ed9f2db940e5be6c53108e2d4790314b979bd2dbf4d7cdbab0d30c969f0cc5' 
  AND token = '0WPaE9LKst1XTH271aY+Wye4oWpcCleAGLaURoaZZS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}