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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c3842b1ce8bc3bc82c33aefc79eac6e26f172c17f55be2e0f0b100b79dc316' 
  AND token = '5L2Lmn17MP1xPmG59BUuy6VBMK9kx3SYCLXzYRBLvQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}