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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49960025363211565335cc2db833bed256105076335b86d8c6cf7f47fb55995' 
  AND token = 'bvnDRAha7F0RcJbAeI7erkqZuWkdY5Y73lWrST9PzEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}