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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9581710db4a6aa216274fde22bd3be6fe0aee6e6aea2e553d587aeb994ea7e6c' 
  AND token = '2pmcp4ZmFuh5yotqVW7NYTrsuL8kqR12ZoEwlsR4kwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}