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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5062e614ad2900a1c27db34d377f9b6ebb00505ecd912774240ccad3d738d3' 
  AND token = 'RK2wboSl4GXHE/rrzPJtDHhnksO19C84HfPthtcs5Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}