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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480869269c588b3abc3778019db7ae13a105eab1a3280e32b77d4d8848ec6e5a' 
  AND token = 's38dRYam9yQglP1NefNwRALkvNDmWVUdm5Uw0/ha3dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}