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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6283c4617c953860ea21a3fcf3cf4b05d5065a6b5d53c061e9a7115c404c30d' 
  AND token = 'LAYY4+jKzY1PkNKRHO6XwG3sGV88EP4gGX9v6uBEO6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}