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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4667eb3e0d1d23df15cc1cdf436d979d727f1935729082facc45be41270cede' 
  AND token = '30e4G0t1xNBfI7xJc7daqutCNKffqdRBvz20L4pv7NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}