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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c223371df121d373418c632f82ad2e857a4bc4d967bbe25129ae2a8b2dc6d065' 
  AND token = 'EgFoHeJHdq/zoEJd8d+Gs6Dp++Wk6bSHwwowxzUn0nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}