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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf2c672a441a687651b8e94e7f2547768a7bcfd8c6a801b7d558d3cd5397725' 
  AND token = 'bfW0+kXoLFOWKBZjMWtJRSN0lcKIENrWtqmb0eSMwkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}