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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b364a4bf813ccd17fe4410a04b19b8f65cc346c0d11e2bd66e7ddfcbe124187' 
  AND token = '4LmJ5lkkydza8RqeZDg+mOBU0JAlhfz4XlDchQvJdSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}