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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca0f12d09d90e283963830ea1734fc78e7937dcf0309a130aa931c2e1fd2f1e' 
  AND token = 'QCg6YjwGOio5uRciUqz4LbmqC32AhdqH5sCu5YsncZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}