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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc7ceb66e28979014ac6b456eddef46b8f91a65c8ef4163e29997c2215dc66d5' 
  AND token = '722mOO4QC8oqcDoBKhsz6jz/UfUjrqka9CAICZUUAbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}