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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce5c4521ed745e431cd48625a8e479393e91743e13bf04625a5870a3bf991b8f' 
  AND token = 'u0Mmk8bfIKAjIcWSICZoV1pRAsxmgDzkv2AtklsvOyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}