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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a782d2e838a256c104e787b77b51db10dcf7a19932f6d2c2d2e89efe6ee554' 
  AND token = 'znAeL0DBfN37ZY3kApSKTv5/ruFJq/DbaKB/MyNdFyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}