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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5563fade875cf1b1eb71cd1e8e69949fa31a2a5a4afb93486f235e42849f636e' 
  AND token = 'Qs5ehD35i1p6CS6msHx2cIVjaDzTnQmeN1kUeHKPanQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}