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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f101c0e54a39f15326582ff23ab0a3d90a2f4911d8e5addd9fa9e4d9fd9bdc0f' 
  AND token = 'Dzc6XnGGXpj0i9C1mEO+kGTHwEz4j/2gThYejQ7G+HU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}