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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d85d70f40246d5acbaa983d509a0e9c7cb6d0d1b5b87a674cffde2b958605a6' 
  AND token = '07IZAuQbLddNLu6gNFoAn+6QLSgDvL9hq2P2Q+JmaA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}