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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ab6fa3751d2e7f4242e6f4014b212b6172fa8b1235c9333635b121911a6184' 
  AND token = '8VRvpVDYk2uEzuu3McxP1wIskwTaTVlOX/+v6T5ibY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}