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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0473bddf411b4df5cf2f97cb7d6a770aec426d2af4cfe6506bef3886a2ef1c7f' 
  AND token = 'MJLyNXbYHYPfbuSCRdSPeRqT+wl/kk9aVplOgyC7BK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}