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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817122a0e45b1dbc957e688450863004ae856a383700e8cd4bca366ea05badca' 
  AND token = 'PbGKNQfY0mGX/nKQ1g/1SN5ggNv05+YzSqfv18Wc41A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}