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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8df8384e0320a109966065943b2f3b9808bfa4aef1f78b0e26e6791bf967de4' 
  AND token = 'rKSD9ACc3dsAWr8HjIA51YWZpiaw6ZZyfzWGuOg0xK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}