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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33554706dda9a1622349aeda8901200a1e31ccfe3b9ad05bac77bda91e1a1304' 
  AND token = '9OCYYMPWMo3YOxP8xBxCS9N4iSiU3HJ78jLkkB1N7vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}