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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa3e446bd7bb012c7aacaabf6e9907f6b6d4f0cbb7c8d08eea04d42208d212be' 
  AND token = 'GdU2YRiyF9Hb04pzX0XbNzjXHpoD0AX+Y1d2AfbrD94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}