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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60d249fce2cb9aa52e2a7027d3510b4aa1070b70cd8a4f1d2849b509787b1c34' 
  AND token = '1CNtVmmsUpc8ZqOKbqU6aXX+LuJ8zeGOTWJFf36L95w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}