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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439b99b64b773c903a3750911cb37e646fc38c1c3d93c42efd755a4c5a18353d' 
  AND token = 'tO5YAHQaX1Oa7/SAhHM2oGa0UTLkRoUrmQ49RalgzmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}