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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c1720eba21cd89196c2ef133e37dfb5c7bfb81d32f1f2c108d8604f3b6878bf' 
  AND token = '+xbIyfcf9lLvZYOQzz6brlLb2YxfcPwcr4Ek7Dwf37g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}