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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe39b29ba6566fa07dd2680244e0a11f7bb9f646ae87d378f8d8819cd845ac68' 
  AND token = 'rXyf00je3sT39YFTOswZ5DTbJdLekW0hl1VuB8/XaJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}