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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d16e2f3a52b68c17545f126ad856335a5d1d2a7feab2ac8c383c205f59aff86' 
  AND token = 'ZsOFCYMcnAlMNHrkZxbN7Dv5FviG5UvhIgu3dABl+2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}