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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63f5d82c4fe00386d0135ad5dffb919d4f12d75b6fd2365d94b07c324335d418' 
  AND token = 'X1Fs2fl1rM3XtQMDggBy/dhEt4Tzmtv6106VAFvYhKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}