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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7106b1f98502158e5b8480c304dcf3a40d21d6ceb96c909fb9406c2f18ea010b' 
  AND token = 'ePng/vdSUV78qZxcCv5+N4s76tzpWc9ygAOh0t9m8/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}