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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f29389c9ff6cf555ab2f6f2b1e98da0a86f24a546f236719eb6e479b8e733bb' 
  AND token = 'r3jo9Fsg6H9ZrnfS00CDA68sg1DhrgCUBMdp/Thzls8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}