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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '559e3892f753989ad3f8761347219b3be9b223386b7e2285d6c3bcde9a90f613' 
  AND token = 'wyBdWRJfsu7XwpXFvZDzlOpA8VOvi1AkXXHActFCo5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}